What is the primary cause of osteomalacia?

Osteomalacia is primarily caused by a deficiency of vitamin D, which plays a crucial role in calcium metabolism and bone health. Without adequate vitamin D, the body cannot absorb sufficient calcium from the diet, leading to softening of the bones due to insufficient mineralization. This deficiency disrupts the balance of bone formation and resorption, resulting in weakened bones that are more prone to pain and fractures.

Inadequate dietary intake of calcium is indeed a concern for bone health; however, the fundamental issue in osteomalacia is primarily related to vitamin D deficiency and not just a lack of calcium. While excessive bone remodeling can affect bone density, it does not specifically address the mineralization defect characteristic of osteomalacia. Infection of the bone, known as osteomyelitis, is a totally different condition and does not contribute to the softening seen in osteomalacia. Thus, vitamin D deficiency is the key factor in this condition, making it the primary cause.