Which statement accurately describes tendons in tendinopathy?

The statement that accurately describes tendons in tendinopathy is that normal organized collagen is replaced with disorganized collagen. In tendinopathy, a degenerative condition often resulting from overuse or injury, the tendon undergoes structural changes. Healthy tendons are characterized by their well-organized collagen fibers, which provide strength and stability. However, during tendinopathy, this organized architecture breaks down, and the collagen becomes disorganized, leading to reduced tensile strength and increased susceptibility to injury. This disorganization is a hallmark of the condition and reflects the tendon’s failure to heal properly after repeated stress.

The other statements do not accurately reflect the changes seen in tendons affected by tendinopathy; for example, tendons generally do not become more elastic nor regenerate more rapidly in this condition, and collagen synthesis does not typically increase—it might actually be impaired or poorly organized.